[Clinical and epidemiological characteristics of tuberculosis in children and adolescents in Armenia].

In Armenia, the incidence of tuberculosis among children aged less than 18 years increased by 53.2% (from 7.9 to 12.1% per 100,000 inhabitants) in 1993 to 2003. On the contrary, the proportion of children and adolescents among all the patients decreased by almost twice (from 13.4 to 8.1%), which is largely due to the reduction in birth rates and to the inadequate detection of minor and local forms of primary tuberculosis. The clinical composition of tuberculosis in 1270 examined patients was the following: tuberculosis of respiratory organs (82.9%); its extrapulmonary forms (14.4%); tuberculous intoxication (2.7%); a concomitance of pulmonary and extrapulmonary tuberculosis (5%). The boy-girl ratio was 2:1. Tuberculosis of intrathoracic lymph nodes was predominant in children aged less than 14 years; infiltrative tuberculosis was prevalent in adolescents. Lung tissue destruction was observed in 15.7%; Mycobacterium tuberculosis was found in 10.2% of the patients. 49.9% of the patients were from the foci of tuberculosis; half of these cases were from the hidden foci of this infection.

[Influence of the medial raphe nucleus damage on discharge activity of the central and bazolateral nuclei of the amygdala]. / Vliianie razrusheniia medial'nogo iadra shva na fonovuiu impul'snuiu aktivnost' neironov tsentral'nogo i bazolateral'nogo iader mindaliny.

It has been revealed pronounced differences between neuronal discharge activity of central and basolateral nuclei of amygdala. After midbrain raphe medial nucleus damage discharge activity of amygdalar nuclei markedly changes, mainly by reciprocal manner. It is suggest that serotonergic afferentations from nucleus raphe to show various influence upon discharge activity of central and lateral nuclei of amygdala.

[Taurine effects on background impulse activity of the internal geniculate body neurons and mesencephalic inferior tubers of white rats]. / Vliianie taurina na fonovuiu impul'snuiu aktivnost' neironov vnutrennogo kolenchatogo tela nizhnikh bugrov chetverokholmiia belykh krys.

Microelectrophysiological and computer techniques were used in the study of background impulse activity (BIA) of the internal geniculate body (IGB) neurons and mesencephalic inferior tubers (MIT) of white rats. Definite differences were found in BIA by regularity, dynamic types and modality of interimpulse histograms. Mean frequency of MIT neuron discharges was 16-17 Hz and was about 3 times higher than in neurons of the IGB. Intraperitoneal injection of taurin noticeably suppressed neuronal activity in both nuclei. The drug reduced mean frequency of background impulse discharges both in MIT and IGB. Thus, taurin produces primarily suppressing modulating effect on neuronal activity of IGB and MIT.